Although andropause is sometimes considered a natural consequence of aging, researchers have a good understanding of the underlying conditions that contribute to the drop in testosterone levels. 

As with other hormone systems, andropause is driven by a disruption in the normal feedback mechanisms that control healthy testosterone production.


A decrease in pituitary gland function, which lowers levels of luteinizing hormone (LH). LH is the main signaling hormone that stimulates the testes to begin testosterone production.


In response to reduced LH levels, the testes become less receptive to LH, which further reinforces the decline in testosterone production.


An increase in the production of sex hormone binding globulin (SHBG). SHBG binds to testosterone in the blood, making it unavailable.

Overall Health Benefits of Semaglutide

  • Promotes weight loss [1-41]
  • Fights type 2 diabetes and lowers blood sugar levels [42-69]
  • Prevents cognitive decline [70-81]
  • Lowers blood pressure [4] [82-88]
  • Lowers the risk of cardiovascular disease [89-96]

Key Takeaways of Semaglutide Guide 2023

  • Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used for the treatment of type 2 diabetes and chronic weigh management. It works by mimicking the effects of the GLP-1 hormone, leading to reduced appetite, increased feelings of fullness, and slower gastric emptying.

  • Semaglutide has demonstrated significant and sustained weight loss in clinical trials, making it a promising option for individuals with obesity. The once-weekly injectable formulation of semaglutide has shown superior weight-loss outcomes compared to placebo and other weight-loss medications.

  • Alongside its effectiveness in weight reduction, semaglutide also helps improve glycemic control and cardiovascular risk factors in people with type 2 diabetes.

  • Semaglutide is typically used as an adjunct to lifestyle changes, including diet and exercise, to achieve optimal weight loss results. As with any medication, it is crucial for healthcare providers to closely monitor patients on semaglutide therapy and adjust the treatment plan as needed.

What is Semaglutide?

Semaglutide, categorized as a GLP-1 agonist, has obtained approval from the U.S. Food and Drug Administration (FDA) under the brand names Ozempic and Rybelsus for managing type 2 diabetes, and as Wegovy for the treatment of excess weight (overweight) and obesity. At higher doses, semaglutide promotes fat loss by suppressing your appetite. When combined with lifestyle modifications such as a healthy diet and exercise program, semaglutide produces amazing results. For this reason, semaglutide has been employe by health care providers for over 15 years in the management of type 2 diabetes.

How does Semaglutide Work?

As a glucagon-like peptide-1 receptor agonist (GLP-1 RA), it increases the secretion of the hormone insulin which helps the cells to effectively utilize energy. This process ensures proper fat storage and decreases blood glucose (blood sugar) levels. Semaglutide also suppresses your appetite and slows gastric emptying by blocking certain chemicals in the brain. This in turn helps promote fat loss.

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